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WASHINGTON, NOV. 19, 2025 — The U.S. Department of Health and Human Services (HHS) today published Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices, its peer-reviewed study of the medical dangers posed to children from attempts to change their biological sex.
The report, released through the Office of the Assistant Secretary for Health, finds that the harms from sex-rejecting procedures — including puberty blockers, cross-sex hormones, and surgical operations — are significant, long term, and too often ignored or inadequately tracked. These conclusions confirm President Trump’s Make America Healthy Again Commission’s findings that unnecessary procedures and long-term health risks such as infertility are the byproduct of the overmedicalization of children.
Before submitting its report for peer review, HHS commissioned the most comprehensive study to date of the scientific evidence and clinical practices surrounding the treatment of children and adolescents for “gender dysphoria.” The authors were drawn from disciplines and professional backgrounds spanning medicine, bioethics, psychology, and philosophy.
HHS invited the American Academy of Pediatrics and the Endocrine Society to contribute their evidence to this report. Both organizations declined to participate.
Source: HHS Releases Peer-Reviewed Report Discrediting Pediatric Sex-Rejecting Procedures | HHS.gov